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diagnosis hematology anemia causes hemolytic rheumatology vasculitis agglutinin champs chestpain classification disease extravascular hemolysis intravascular low management mnemonic vasculitides weightloss
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... A - Atypical HUS ... @AnnKumfer #Hypocomplementemia ... #Low #Complement ... Mnemonic #diagnosis #differential
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Diagnosis Algorithm ... Warm AIHA • Cold ... perfringens - Complement-Mediated ... • Cold AIHA ... MAHA (TTP, DIC, HUS
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitis - Skin, glomeruli ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... : - Kidneys: glomerular ... against MPO • Complement
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Positive Coombs testing ... post infectious setting ... Mycoplasma, EBV, HIV ... younger pts) Differential ... temperatures by fixing complement
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... Diagnosis Algorithm ... Agglutination - Cold ... DIC, TTP, HELLP, HUS ... workup #hematology #testing
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... • Kidneys: Non-glomerular ... HTN • Check: HBV ... Elevated AST ALT • Hypocomplementemia ... Vasculitis) • Hypocomplementemic
Chest Pain Diagnosis and Management Algorithm STEMI: - Hx: Pressure like CP, Radiation to arm/jaw, CAD risk
and Management Algorithm ... onset, severe, tearing ... caustic ingestion, HIV ... , Dyspnea, H/O COPD ... #differential
Weight Loss - Differential Diagnosis Algorithm Decreased Intake: • GI illness (upper and lower) • Psychiatric (Depression,
Weight Loss - Differential ... Diagnosis Algorithm ... Psychiatric (Depression, eating ... COPD) • Chronic ... Diabetes Mellitus • HIV
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