6 results
Pathophysiology of Hypocomplementemic Urticarial Vasculitis

C1q/anti-C1q antibiody ->
Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology of Hypocomplementemic ... Complex Formation - Complement ... and perivascular inflammatory ... TerrierBen #Hypocomplementemic
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... Syndrome: - Ocular inflammatory ... against MPO • Complement ... #rheumatology #classification
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
histamine and other inflammatory ... antigens, leading to complement ... they activate complement ... allergy #table #classification ... #comparison
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
unique or multiple inflammatory ... rheumatoid factor), ± hypocomplementemia ... Disease #diagnosis #management
IGG-4 RELATED DISEASE

WHAT?
 • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
ureters • Aorta: Inflammatory ... - ↑ IgE, ↓ complement ... • Classification ... mimics excluded MANAGEMENT ... IGG4 #Diagnosis #Management
Diets and Inflammatory Bowel Disease (IBD)
Diet affects IBD by 3 mechanisms
1. Microbiome ( ↓ diversity)
2. Mucosal
Diets and Inflammatory ... Immune response (↑ inflammatory ... • Nutrition as complement ... IBD #Nutrition #comparison ... #table #management