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differential nephrology endocrinology adrenal hematology workup cardiology hyponatremia insufficiency management sodium causes criticalcare hypokalemia amenorrhea clinical deficiency disease evaluation foamed
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... @AnnKumfer #Hypocomplementemia ... #Low #Complement ... CHAMPS #Mnemonic #diagnosis
Adrenal Insufficiency Differential Diagnosis Algorithm Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Insufficiency Differential Diagnosis ... Algorithm Clinical ... , hypoglycemia Testing ... Low Cortisol Response ... insufficiency • Low
Diagnosis Adrenal Insufficiency - Algorithm Step 1) Screening Test: 6-8AM Cortisol Level - Early morning cortisol levels
Insufficiency - Algorithm ... specificity for AI (but low ... require Cosyntropin testing ... - Low ACTH is ... #Diagnosis #ACTH
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH Early am cortisol < 3
Insufficiency Diagnosis ... Algorithm - Evaluation ... then go to stim testing ... primary AI - Low ... #Algorithm #ACTH
Complement Deficiency Testing Algorithm • Normal CH50 and AH50 AND High suspicion for complement deficiency •
Complement Deficiency ... Testing Algorithm ... #Deficiency #Testing ... #Algorithm #hematology ... #diagnosis
Primary Adrenal Insufficiency: • ACTH stimulation test - Synthetic ACTH does not stimulate cortisol secretion because
between 8 and 9 AM - Low ... aldosterone - Low ... - Low, because ... Evaluation #laboratory #diagnosis ... #testing #endocrinology
Benign Adrenal Mass - Differential Diagnosis Algorithm Hyperplasia - Often Bilateral • Congenital Adrenal Hyperplasia • ACTH
- Differential Diagnosis ... Algorithm Hyperplasia ... Hyperplasia • ACTH ... Dependent • ACTH ... High DHEAS • Low
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... (Low levels mixed
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low ... Complement: Post-strep ... Idiopathic • Normal Complement ... #differential #diagnosis ... #algorithm #rheumatology
Syphilis Serologic Testing - Treponemal and Non-Treponemal Testing Algorithms Treponemal Testing: • Confirmatory or Screening - Detection
Syphilis Serologic Testing ... Non-Treponemal Testing ... Algorithms Treponemal ... Definitive • Low ... #diagnosis #Treponemal
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