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diagnosis rheumatology allergy hypersensitivity reactions table types coccidioidomycosis comparison criteria differential disease erythematosus eularacr infectiousdiseases lupus pathophysiology phenotypes related sle
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... node), high serum IgG4 ... rheumatoid factor), ± hypocomplementemia ... with increased IgG4 ... Disease #diagnosis #management
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... Vasculitis: • Fevers ... against MPO • Complement ... #rheumatology #classification
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
, seasonal hay fever ... antigen, leading to complement ... Type Ill - IgG and ... Complement activation ... Hypersensitivity #Types #Classification
IGG-4 RELATED DISEASE WHAT? • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
IGG-4 RELATED DISEASE ... - ↑ IgE, ↓ complement ... • Classification ... mimics excluded MANAGEMENT ... #Management #Rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Constitutional domain: Fever ... Anticardiolipin IgG ... or anti-ß2GPI IgG ... anticoagulant • Complement
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Anaphylaxis, Hay fever ... - Mediators: IgG ... Mechanism of Action: IgG ... they activate complement ... allergy #table #classification
Coccidioidomycosis (Valley Fever) - Diagnosis and Management Summary WHAT? • Coccidioidomycosis due to Coccidioides immitis or Coccidioides
Diagnosis and Management ... known as valley fever ... analysis using complement ... check for IgM and IgG ... #Diagnosis #Management
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