62 results
The Causes of Cirrhosis

#Diagnosis #Differential #Hepatology #Cirrhosis #Causes
The Causes of Cirrhosis ... #Diagnosis #Differential ... #Hepatology #Cirrhosis ... #Causes
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Liver Enzymes - Differential ... Infiltrative • Cirrhosis ... Others #LFTs #Hepatology ... #LiverEnzymes #Differential ... Diagnosis #Algorithm #Causes
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
Jaundice - Differential ... • Gilbert's Syndrome ... - Usually has Duct ... Diagnosis #Algorithm #Causes ... #Hepatology #bilirubinemia
Disorders of the Hepatic and Mesenteric Circulation

Platelets in Cirrhosis
Hypercoagulability in Cirrhosis
Bleeding in Cirrhosis
Portal Vein Thrombosis (PVT)
Mesenteric
Platelets in Cirrhosis ... Bleeding in Cirrhosis ... ) Budd Chiari Syndrome ... Circulation #Disorders #Hepatology ... #Gastroenterology
Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
Etiologies of Cirrhosis ... disease (Budd-Chiari syndrome ... #Diagnosis #Differential ... #Hepatology #Cirrhosis ... #Causes
Classification of Jaundice
Unconjugated hyperbilirubinemia (predominantly indirect bilirubin)
 • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
drugs, biliary cirrhosis ... carcinoma of biliary duct ... pressure on bile duct ... #unconjugated #differential ... #causes
Causes of Portal Hypertension According to Site of Vascular Obstruction
1) Prehepatic pre-sinusoidal: Portal vein thrombosis due
Causes of Portal ... post-sinusoidal: Budd-Chiari syndrome ... portalhypertension #phtn #differential ... #diagnosis #causes ... #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... and hepatorenal syndrome ... Clues to non-cirrhotic ... #Diagnosis #causes ... #hepatology
Ascites - Differential Diagnosis
Chronic liver disease (cirrhosis or chronic hepatitis) - 80%
Underlying malignancy - 10%
Congestive heart
Ascites - Differential ... liver disease (cirrhosis ... failure - 3-5% Cirrhosis ... Fitz-Hugh-Curtis syndrome ... #Diagnosis #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary Cirrhosis ... causes cholestasis ... → Cirrhosis/Liver ... Differential ... diagnosis #workup #hepatology