145 results
Type 2 Diabetes - Screening, Diagnosis and Management Algorithm
Lifestyle  Modifications (Diet and Exercise) -> Start
-> Start Oral Hypoglycemic ... Second Oral Hypoglycemic ... Recurrent severe hypoglycemia ... relative with DM2 ... Management #algorithm #DM2
Differential Diagnosis of Transient Ischemic Attack and Stroke
 - TIA/stroke 
 - Seizure 
 - Hypoglycemia/hyperglycemia
- Seizure - Hypoglycemia ... /hyperglycemia ... Differential #Diagnosis #Neurology
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS)
Absolute Insulin deficit:
 - Type I DM:
Pathophysiology ... deficit: - Type I DM ... produced - Type II DM ... food binges, etc Hyperglycemia ... #dka #hhs #pathophysiology
Diabetes – diabetic nephropathy
Majority of the literature in the area is applied to the diabetic nephropathy
- Chronic hyperglycemia ... hyperfiltration - Hyperglycemia ... - Cytokines #Pathophysiology ... #Nephrology #CKD
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Does not cause hypoglycemia ... mL/minute/1.73 rm2 ... mL/minute/1.73 m2 ... Pharmacology #Summary #DM2
Causes of Seizures - Differential Diagnosis Algorithm
Unprovoked - Epilepsy:
 • Focal: Simple, Complex
 • Generalized: Absence,
• Metabolic: Hypoglycemia ... , Hyperglycemia, ... Algorithm #Causes #neurology
Diabetes Pathophysiology and Medication Targets

The ominous octet is one concept that summarizes the different pathophysiologic pathways
Diabetes Pathophysiology ... the different pathophysiologic ... pathways that lead to hyperglycemia ... #Diabetes #Pathophysiology
INSULIN CONVERSION

Total daily dose of insulin (TDD) =
& most type 2 DM ... or at risk for hypoglycemia ... insulin #diabetes #hyperglycemia ... #dm2 #basalinsulin
Causes of Secondary / Provoked Seizures - Differential Diagnosis Algorithm
Febrile
Infection
 • Sepsis
 • Encephalitis
 • Meningitis
Metabolic
Metabolic • Hypoglycemia ... • Hyperglycemia ... Provoked #Seizures #Neurology
Sulfonylureas - Pharmacology Summary
Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
: Weight gain, Hypoglycemia ... Pharmacology #Summary #DM2