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differential rheumatology algorithm anesthesiology capillary cerebritis clarksons cns complexes encephalopathy erythematosus evaluation gitelman gravis hyperthermia leak low lupus myasthenia pathophysiology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... • Autoimmune disease ... Rhabdomyolysis Treatment ... • Magnesium ... #diagnosis #nephrology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
Neuroleptic malignant syndrome ... • Serotonin syndrome ... Anticholinergic syndrome ... Sympathomimetic syndrome ... #Checklist #Diagnosis
Causes of Hypomagnesemia • Redistribution: IV glucose, Correction of diabetic ketoacidosis, IV hyperalimentation, Refeeding after starvation,
Causes of Hypomagnesemia ... Postparathyroidectomy (hungry bone syndrome ... metastasis (hungry bone syndrome ... Endocrine disorders: Syndrome ... #diagnosis #nephrology
Evaluation and Management of Hypokalemia Hypokalemia is often asymptomatic. Evaluation begins with a search for warning signs
Most cases of hypokalemia-induced ... of concurrent hypomagnesemia ... important because magnesium ... depletion impedes potassium ... #Diagnosis #Hypokalemia
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 Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Compartment syndrome ... Neuroleptic malignant syndrome ... or compartment syndrome ... #Management #causes ... #treatment #nephrology
Premature Ventricular Complexes (PVC's) - Summary Framework Why PVCs? Can be the first manifestation of cardiac
Inherited arrhythmia syndromes ... syndrome, ARVC) ... • Hypokalemia ... more intensive treatment ... #differential #cardiology
Clarkson’s Disease - Capillary leak syndrome Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Capillary leak syndrome ... Hypovolemia: Asthenia ... edema, compartment syndrome ... Capillary #leak #syndrome ... #diagnosis #management
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
thyroid, Sjogren syndrome ... “dropping head syndrome ... - Kearns-Sayre syndrome ... Eaton myasthenia syndrome ... #management #neurology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... autoantibodies that will cause ... Erythematosus #SLE #CNS #neurology ... #management #treatment
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Encephalopathy Syndrome ... Clinico-Radiological Syndrome ... syndrome by 24 ... #diagnosis #management ... #neurology
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