15 results
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... intracellular calcium causes ... - Hyperkalemia ( ... (or low potassium ... #Pharmacology #
Hyponatremia Diagnosis Algorithm
UOsm ≥ POsm - Vasopressin-Dependent
 • UNa < 20 mEq/L - Appropriate (↓ EABV)
EABV) - Consider: Hypovolemia ... , Heart failure, ... Primary polydipsia, Low ... #algorithm #causes ... #nephrology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
Present (Uosm ≥100): Hypovolemia ... renal perfusion (Heart ... #differential # ... diagnosis #table ... #sodium #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Differential Diagnosis ... Management Summary Causes ... Hyperuricemia • Hyponatremia ... Monitor potassium ... #treatment #nephrology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Heat Stroke - Differential ... Dehydration - Loss of sodium ... /Potassium - Extreme ... illness → Hypernatremia ... #differential #
Hyponatremia - Differential Algorithm
Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP
Hypotonic Hyponatremia: 
 • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
Hyponatremia - Differential ... : • Hypovolemia ... Hypervolemia: Congestive Heart ... #nephrology #sodium ... #low
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... : • Digoxin ... lysis syndrome - Rhabdomyolysis ... diagnosis #causes ... #nephrology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Differential Diagnosis ... Monitor potassium ... Dialysis for severe hyperkalemia ... #Differential # ... Management #Summary #causes
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... : • Digoxin ... lysis syndrome - Rhabdomyolysis ... diagnosis #causes ... #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
thiazide-sensitive sodium ... alkalosis • Normal or low ... ratio 0.5%) Differential ... • Seizures • Rhabdomyolysis ... Syndrome #diagnosis #nephrology