11 results
Disorders of Pigmentations - Hypopigmentation and Hyperpigmentation - Differential Diagnosis Algorithm

HYPOPIGMENTATION
Diffuse Congenital - Generalized hypopigmentation of
Diagnosis Algorithm ... #disorders #skin ... #dermatology #Differential ... #Diagnosis #Algorithm ... #causes
Skin Hyperpigmentation - Differential Diagnosis Algorithm
Diffuse:
 • Tanning
 • Adverse cutaneous drug eruption
 • Addison's disease
Skin Hyperpigmentation ... Diagnosis Algorithm ... #disorders #skin ... #dermatology #Differential ... #Diagnosis #Algorithm
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Pruritus - Generalized ... Differential Diagnosis ... Myelodisplastic syndrome ... #primary #secondary ... Diagnosis #Algorithm
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... purple, hemorrhagic skin ... #Diagnosis #hematology ... #rheumatology #
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Testing Algorithm ... • Screen for secondary ... symptoms (eg, skin ... #Algorithm #Differential ... #diagnosis #hematology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Skin Lesion - Differential ... Diagnosis Algorithm ... #secondary #systemic ... Diagnosis #Algorithm ... #causes
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... - Purpura - Skin ... Type III Often Secondary ... Henoch-Schönlein purpura) • Cutaneous ... classification #rheumatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
• Painful or pruritic ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... #rheumatology # ... hematology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
gangrenosum • Cutaneous ... hypertrichosis, hyperpigmentation ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
sweats, bleeding • Pruritis ... bone marrow and secondary ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis