Hyponatremia Differential workup dermatology hematology oncology hemolytic causes primary generalized classification diagnosis mds intravascular

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Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
• Mechanical Trauma (Microangiopathic hemolytic anemia):

Extravascular Causes ... usually IgM) (e.g. primary ... #Hemolytic #Intravascular ... #Causes #differential ... #diagnosis #hematology

Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production:
• Increased Reticulocytosis/polychromasia
• Erythroid

Hemolysis - Diagnostic ... Algorithm and Causes ... #Algorithm #Differential ... #Causes #Workup ... #Hematology #Diagnosis

Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
• Enzyme deficiencies ex. G6PD, pyruvate kinase
• Hemoglobinopathies

Differential Diagnosis ... IVIG infusion Intravascular ... #Diagnosis #causes ... #classification ... #hematology

Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
- Prior platelet count, family

Diagnosis and Workup ... Infection exposure (l MD ... unclear, or if a primary ... #Diagnosis #Causes ... #Workup #hematology

TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A

activity is the diagnostic ... available for rapid diagnosis ... reflection of intravascular ... WBC count and differential ... #Workup #Hematology

Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It

nodosum • Immune hemolytic ... ) Classification ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... #hematology #oncology

Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly

formed or don’t work ... Workup: • Complete ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology

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