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Pathophysiology of hypotonic hyponatremia

by Helbert Rondon, MD @NephroMD

#hypotonic #hyponatremia #nephrology #algorithm #Pathophysiology
Pathophysiology of hypotonic ... hyponatremia ... @NephroMD #hypotonic ... #hyponatremia #
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
Modified Hyponatremia ... Algorithm Hypertonic ... Hyponatremia: Hyperglycemia ... Urologic irrigants Hypotonic ... Hyponatremia:
Goals and limits for treatment of Hyponatremia Stratified by duration and risk of Osmotic Demyelination Syndrome
for treatment of Hyponatremia ... Hyponatremia (duration ... Otherwise, hypertonic ... Hyponatremia (duration ... limits #management #hyponatremia
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Causes of Hypernatremia ... water Extrarenal hypotonic ... salt intake: • Hypertonic ... administration #Hypernatremia
Hypo-osmolar Hypotonic HypoNatremia Algorithm (Serum Na+ < 135 meq/L, serum Osm < 275 mosm/kg)
Assess Volume Status,
Hypo-osmolar Hypotonic ... HypoNatremia Algorithm ... Urine Osm #Hyponatremia ... #Differential #Hypotonic
Hyponatremia - Differential Algorithm
Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP
Hypotonic Hyponatremia: 
 • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
Hyponatremia - Differential ... Algorithm Isotonic Hyponatremia ... , Recent TURP Hypotonic ... Hyponatremia: ... Hypothyroidism Hypertonic
Visualizing Hypotonic Hyponatremia

 • UNa reveals RAAS activity.
 • UOsm reveals ADH activity.
 • ADH secretion
Visualizing Hypotonic ... Hyponatremia ... COREIMpodcast #Hypotonic ... #Hyponatremia #
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
Physiologic Approach to Hypotonic ... Hyponatremia The ... have a case of hypotonic ... hyponatremia, give ... #Hyponatremia #
Hyponatremia with Severe Symptoms - Management Algorithm with Hypertonic Saline
The goal of acute management is to
Hyponatremia with ... Algorithm with Hypertonic ... kidney_boy #Hyponatremia ... Algorithm #treatment #Hypertonic
Hyponatremia Correction
1. Indications for Hypertonic Saline: seizure, coma, focal findings
   - typically occurs with
Hyponatremia Correction ... Indications for Hypertonic ... Overcorrection of Hyponatremia ... MetroHealth_EM #Hyponatremia