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adrenal diagnosis differential stimulation workup ai causes cosyntropin evaluation highcalcium hypercalcemia laboratory management pathophysiology stimtest test testing
Adrenal Insufficiency - Differential Diagnosis Workup Algorithm Primary Adrenal Insufficiency: • Autoimmune primary adrenal insufficiency • Adrenoleukodystrophy,
Primary Adrenal ... • Autoimmune primary ... or tuberculosis Secondary ... apoplexy • Isolated ACTH-deficiency ... #endocrinology
Adrenal Insufficiency Differential Diagnosis Algorithm Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Differential Diagnosis Algorithm ... - Primary adrenal ... - Secondary adrenal ... Differential #Diagnosis #Algorithm ... #endocrinology
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH Early am cortisol < 3
Adrenal Insufficiency ... Diagnosis Algorithm ... AI #Adrenal #Insufficiency ... #Diagnosis #Algorithm ... #Test #Endocrinology
Primary vs Secondary Adrenal Insufficiency - Pathophysiology Primary AI = adrenal glands themselves are the problem. This
Primary vs Secondary ... Adrenal Insufficiency ... be low, while ACTH ... Low ACTH leads to ... Pathophysiology #endocrinology
Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm ACTH-Dependent (Secondary): • Pituitary Dysfunction • Hypothalamic Dysfunction ACTH-Independent (Primary):
Causes of Adrenal Insufficiency ... ACTH-Dependent ... (Secondary): • ... (Primary): • Autoimmune ... #Causes #endocrinology
Diagnosis Adrenal Insufficiency - Algorithm Step 1) Screening Test: 6-8AM Cortisol Level - Early morning cortisol levels
Diagnosis Adrenal Insufficiency ... - Algorithm ... Differentiate primary ... vs secondary AI ... #Endocrinology
Primary Adrenal Insufficiency: • ACTH stimulation test - Synthetic ACTH does not stimulate cortisol secretion because
Primary Adrenal ... autoimmune-mediated primary ... antibody test Secondary ... test - If the secondary ... diagnosis #testing #endocrinology
Adrenal Insufficiency Diagnosis Algorithm Clinical features: - Weight loss, anorexia, Weakness, fatigue, GI distress - Hypotension,
Diagnosis Algorithm ... skin (due to high ACTH ... , only seen in PRIMARY ... findings (see algorithm ... Stimulation #StimTest #Endocrinology
Adrenal Insufficiency - Diagnosis and Management Summary Primary Adrenal Insufficiency: Most Common Cause in the US: Autoimmune Adrenalitis Other
Management Summary Primary ... is absent (low ACTH ... ACTH STIM TEST: ... #Primary #Secondary ... Diagnosis #Management #Endocrinology
Hypercalcemia - Differential Diagnosis Algorithm Primary Hyperparathyroidism • Adenoma • Hyperplasia • MEN 1 and 2A Tertiary Hyperparathyroidism
Differential Diagnosis Algorithm ... Primary Hyperparathyroidism ... long-standing secondary ... Immobilization • Adrenal Insufficiency ... #Endocrinology
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