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diagnosis immunocompromised algorithm causes humoral immunity immunology infections asplenia cascade diagram druginduced edema fever glomerulonephritis gonorrhea hematology immunecompromised immunodeficiency infectiousdiseases
Infectious Risks in Asplenia and Deficiencies in Humoral Immunity and Complement - Venn Diagram Humoral Immunity: •
and Complement ... Diagram Humoral Immunity ... T and B cells Complement ... PrathitKulkarni #complement ... immunocompromised #infections #differential
Inflammatory Cascade: Pathogenesis and Clinical Findings Continued Innate Immunity • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Continued Innate Immunity ... dead tissue • Complement ... destruction Acquired Immunity ... activation of complement ... #Inflammation #pathophysiology
Infections in Immunocompromised Patients - Differential Diagnosis Summary Innate Immunity: • Neutropenia • Phagocytic Deficiencies • Complement
Immunocompromised Patients - Differential ... Summary Innate Immunity ... Deficiencies • Complement ... Cell-Mediated Immunity ... Immunocompromised #Infections #differential
Humoral Immunity - Pathogenesis and Clinical Findings Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
Humoral Immunity ... contribute to immunity ... proliferate and differentiate ... exposure #Humoral #Immunity ... #pathophysiology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... staining): • Low Complement ... Idiopathic • Normal Complement ... Glomerulonephritis #Vasculitis #differential
Gonorrhea: Pathophysiology - Neonatal Transmission -> Direct contact of patient mucosa with mother's infected mucosa while
Gonorrhea: Pathophysiology ... to avoid host immunity ... activation of complement ... #Gonorrhea #Pathophysiology
Drug-Induced Edema Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
Activation of the complement ... Medication #Causes #Differential ... #Pharmacology #Pathophysiology
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm Structural Defect - Asplenia/HypospIenism • Bacteremia/Septic
Immunocompromised Host - Differential ... Cell Mediated Immunity ... Periodontal Disease Complement ... ImmuneCompromised #Differential
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