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workup anesthesia intraoperative hematology differential treatment cardiac hemophagocytic lymphohistiocytosis airway causes criticalcare disease hyperthermia product reactions anaphylaxis arrest arthritis bloodloss
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... • Clinical: fever ... , ↓ Fibrinogen level ... #management #treatment ... #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
following: • Fever ... lymph node, or liver ... If no response HLH ... #management #treatment ... #hematology
Endocarditis checklist Initial evaluation • Peripheral blood cultures (three sets at three different sites) • Additional culture
Endocarditis checklist ... • Persistent fever ... #Endocarditis #checklist ... #criticalcare #diagnosis ... #management
Intraoperative Massive Blood Loss - Guidelines for Crises in Anaesthesia Expected or unexpected major haemorrhage ❶ Call for
equipment. ❽ Discuss management ... haematologist if ... BloodLoss #Hemorrhage #Anesthesiology ... Intraoperative #Checklist ... #Diagnosis #Management
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
in Anaesthesia If ... • Intracranial blood ... Differential #Causes #Anesthesiology ... #Anesthesia #Checklist ... #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... diagnostic consideration ... Diagnostic Criteria ... Approach • Initial management ... #Management #Hematology
Intraoperative Circulatory Embolus - Guidelines for Crises in Anaesthesia Causes: thrombus, fat, amniotic fluid, air/gas. Signs: hypotension, tachycardia,
Tell surgeon to flood ... field to below level ... Embolism #VTE #Anesthesiology ... Intraoperative #Checklist ... #Diagnosis #Management
Intraoperative Sepsis - Guidelines for Crises in Anaesthesia Severe sepsis (hypotension persisting after initial fluid challenge of
of 30ml.kg-1 or blood ... Discuss ongoing management ... anaesthesia #Sepsis #Anesthesiology ... Intraoperative #Checklist ... #Diagnosis #Management
Mains Electricity Failure - Guidelines for Crises in Anaesthesia Unexpected total power failure is rare and unpredictable.
(Box A): • If ... the pulse and blood ... Electricity #Failure #Anesthesiology ... Intraoperative #Checklist ... #Diagnosis #Management
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Polyarthritis: • Blood ... : • Complete blood ... (to support a diagnosis ... #testing #Rheumatology
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