27 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... , ↓ Fibrinogen level ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
following: • Fever ... • Bicytopenia Treatment ... If no response HLH ... #management #treatment ... #hematology
Pancreatitis management checklist 
Evaluation to guide etiology & management 
 - RUQ ultrasound 
 - Calcium
checklist Evaluation ... ultrasound - Calcium level ... - Triglyceride level ... #Diagnosis #Management ... #CriticalCare
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
ALT ↑ bilirubin level ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
regarding the diagnosis ... and treatment of ... should be TS and SF level ... hemochromatosis #algorithm #diagnosis ... #management #hepatology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Symptomatic anemia Diagnosis ... megaloblastic anemia Treatment ... neutropenic fever ... #management #treatment ... #hematology
Endocarditis checklist
Initial evaluation
 • Peripheral blood cultures (three sets at three different sites)
 • Additional culture
Endocarditis checklist ... • Persistent fever ... #Endocarditis #checklist ... #criticalcare # ... diagnosis #management
Kawasaki Disease (KD) - Diagnosis and Management Summary

Kawasaki Disease (KD) is the most common vasculitis of
Disease (KD) - Diagnosis ... and Management ... KD #vasculitis #rheumatology ... #pediatrics #diagnossi ... #management #treatment
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Life-threatening ... synovitis (40%) Treatment ... Disease #AOSD #rheumatology ... #diagnosis #management ... #treatment
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Treatment - Mild ... : NSAIDS Treatment ... • If uncontrolled ... #rheumatology # ... management