19 results
Validation of the Step-By-Step Approach to Febrile Infants

#Diagnosis #Management #Pediatrics #Peds #Febrile #Infant #StepByStep #Algorithm #LP
Infants #Diagnosis ... #Management #Pediatrics ... #Peds #Febrile ... #Infant #StepByStep ... Stratification #Fever
Clinical Algorithm for Emergency Department Evaluation and Management of UTI in Febrile Infants and Young Children

Urinary
Clinical Algorithm ... Evaluation and Management ... of UTI in Febrile ... UTI #Algorithm #Diagnosis ... #Management #Febrile
“Step by Step” – the new kid on the block – aims to risk stratify this
“low risk” an infant ... CRP < 20 mg/L #Diagnosis ... #Management #Pediatrics ... #Peds #Febrile ... #Infant #StepByStep
The Febrile Infant Step-by-Step Algorithm
This is an algorithm developed by European emergency physicians to identify low-risk
The Febrile Infant ... 92.0% and 46.9% #Diagnosis ... #EBM #Management ... #Pediatrics #Peds ... #Febrile #Infant
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... frequently affects infants ... acute or subacute febrile ... #management #treatment ... #hematology
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
• Leukocytosis Diagnosis ... extremities during febrile ... • If uncontrolled ... #rheumatology # ... management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... , ↓ Fibrinogen level ... #management #treatment ... #summary #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Prophylaxis: • Attempt if ... high risk if WBC ... Subacute-Acute: • Common: fever ... Rare: DAH, acute febrile ... #management #hematology
Evaluation of suspected incomplete Kawasaki Disease

1. AHA consensus recommendations
2. Infants ≤6 months old on day ≥7
Infants ≤6 months ... they have no clinical ... those >day 10 with clinical ... #Diagnosis #Peds ... #Pediatrics #Kawasaki
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... Treatment: - If ... febrile, give abx ... Syndrome #TLS #diagnosis ... #management #hematology