17 results
hematology algorithm disease hemophagocytic hlh lymphohistiocytosis antibiotics causes fever lp oncology peds product reactions risk stepbystep stills stratification syndrome adult
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Life-threatening ... synovitis (40%) Treatment ... #rheumatology # ... diagnosis #management ... #treatment
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... “low risk” an infant ... CRP < 20 mg/L #Diagnosis ... #Management #Pediatrics ... #Peds #Febrile
The Febrile Infant Step-by-Step Algorithm This is an algorithm developed by European emergency physicians to identify low-risk
The Febrile Infant ... empiric antibiotic treatment ... #EBM #Management ... #Pediatrics #Peds ... #Febrile #Infant
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
frequently affects infants ... acute or subacute febrile ... If no response HLH ... #management #treatment ... #hematology
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
extremities during febrile ... • If uncontrolled ... Stills #disease #AOSD ... #diagnosis #rheumatology ... #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... , ↓ Fibrinogen level ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Suspected catheter-related bloodstream infection - Management Algorithm • Temperature 37.8 C • Rigors
purulence Obtain blood ... • Persistent fever ... options and is: • Afebrile ... Hernodynamically stable after treatment ... Algorithm #CRBSI #diagnosis
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... organ damage • Treatment ... : - If febrile ... Syndrome #TLS #diagnosis ... #management #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Subacute-Acute: • Common: fever ... Rare: DAH, acute febrile ... Renal Failure Treatment ... #management #hematology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
in Anaesthesia If ... Treatment depends ... devices, especially infants ... Anesthesia #Checklist #Diagnosis ... #Management #Workup
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