6 results
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
Clozapine Toxicology ... metabolized in the liver ... be tapered off if ... #Toxicology #Toxicity ... #Diagnosis #Pharmacology
Therapeutic Drug Level Monitoring 
Carbamazepine - Sample immediately before next dose (trough) 
Clozapine - Sample immediately
dose (trough) Clozapine ... or at anytime if ... toxicity suspected ... Therapeutic #Ranges #Toxicology ... #Pharmacology #
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
Salicylate Toxicity ... Consider if: ... , Diaphoresis, Pulmonary ... Toxic Salicylate Level ... #Toxicology #diagnosis
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
Amiodarone half life ... Fever 4. ... pneumonia - Pulmonary ... #Pulmonary #diagnosis ... #management #Toxicology
Digoxin Pharmacology and Monitoring

 • Digoxin’s half-life is 30-45 hours in healthy adults
 • When monitoring
Digoxin Pharmacology ... Digoxin’s half-life ... Kat_Watson #Digoxin #Pharmacology ... #Monitoring #toxicology ... #management #toxicity
Methotrexate Toxicology 

Intravenous leucovorin (folinic acid) treatment serves as a cofactor necessary for synthesis of thymidylate
Methotrexate Toxicology ... evidence of marrow toxicity ... Leucovorin #Antidote #Toxicology ... #Toxicity #Management ... #Pharmacology