7 results
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's Disease ... Life-threatening ... low ferritin, arthritis ... #AOSD #rheumatology ... #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
juvenile idiopathic arthritis ... erythematosus [SLE], AOSD ... ALT ↑ bilirubin level ... #Diagnosis #Management ... #Hematology #Rheumatology
Septic Arthritis - Diagnosis and Management Summary
Clinical Exam: hot, swollen, pain with passive AND active ROM
Diagnosis and Management ... active ROM +/- fever ... necrosis, Lyme disease ... Workup: arthrocentesis ... 90% sensitive in pediatrics
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
early evening • Arthritis ... • If uncontrolled ... #AOSD #diagnosis ... #rheumatology # ... management
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Approach to Joint ... acute rheumatic fever ... ), RA, crystal disease ... Inflammatory, crystalline disease ... #approach #workup
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
H's" especially if ... Crowned Dens Syndrome ... acute neck pain, fever ... #Rheumatology # ... diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... hyperinflammatory syndrome ... ▪ Autoimmune diseases ... Treatment Approach ... #Hematology #HemeOnc