22 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
juvenile idiopathic arthritis ... • HLH Labs: ... ALT ↑ bilirubin level ... #Diagnosis #Management ... #Hematology #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
, ↓ Fibrinogen level ... • Autoimmune diseases ... Adult-onset Still disease ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... age, however the disease ... If no response HLH ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
should be TS and SF level ... of liver disease ... and hematologic ... If other causes ... algorithm #diagnosis #management
Septic Arthritis - Diagnosis and Management Summary
Clinical Exam: hot, swollen, pain with passive AND active ROM
Diagnosis and Management ... active ROM +/- fever ... necrosis, Lyme disease ... Workup: arthrocentesis ... 90% sensitive in pediatrics
Kawasaki Disease (KD) - Diagnosis and Management Summary

Kawasaki Disease (KD) is the most common vasculitis of
Kawasaki Disease ... , Tachycardia, Arthritis ... , Cough • +/-Nausea ... KD #vasculitis #rheumatology ... #pediatrics #diagnossi
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Studies in Rheumatic Diseases ... back pain) • HLA-B27 ... #Rheumatic #Disease ... #laboratory #workup
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Algorithm Vascular Causes ... vein: Budd-chiari syndrome ... PBC, PSC, IgG4, HLH ... • Gilbert's syndrome ... diagnosis #algorithm #hepatology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... caused by uncontrolled ... syndrome, a search ... ▪ Autoimmune diseases ... #Hematology #HemeOnc
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... • Immunologic Workup ... • Immunologic Workup ... Evolution: Chronic disease ... #diagnosis #management