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apml differentiation dress hematology induced lung oncology toxicity toxicology
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
treatment) • Can ... respiratory distress syndrome ... Exclude other causes ... macrophages Treatment ... #diagnosis #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... fluid overload, PCC ... #management #hematology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Edema in 70% of cases ... disease: symptomatic treatment ... Hospital of Baltimore IM ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis
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