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Hemolysis Classification - Intrinsic and Extrinsic Causes Commentary: Another way to think of immune hemolysis would be
would include IVIG-mediated ... Intrinsic #Extrinsic #Differential
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... snake bites • IVIG ... Hemolytic #Anemia #Differential
Drug Induced Kidney Injury • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy • Osmotic
tubules: Hetastarch, IVIG ... #KidneyInjury #differential
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
positives: - IVIg ... BAL GM does not differentiate ... never +GM) - IVIg
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Resolution > 15 days Differentials ... : Cyclosporin, IVIg
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
False positives: IVIG ... in BAL does not differentiate ... almost never +), IVIg
Myasthenic Crisis Checklist - Myasthenia Gravis Evaluation - Chest X-ray and lung ultrasound (exclude other lung
Phos), CBC with differential ... Plasma exchange/lVIG ... unavailable may use IVIG
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
life-threatening Differential ... Immunomodulating Treatments: IVIG
DEMYELINATING DISEASES OF THE CENTRAL NERVOUS SYSTEM What Are Demyelinating Diseases? • Conditions that damage myelin, the protective
Treatment: Steroids, IVIg ... long-term with IVIg ... IV steroids ± IVIg ... neurology #CNS #Differential
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Immunomodulatory agents: IVIG ... management #neurology #differential
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