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diagnosis liver differential management algorithm causes injury lfts transaminitis gastroenterology hematology hepatitis medications function interpretation lupus pathophysiology rheumatology tests thrombocytopenia
Drug-Induced Liver Injury - Pathophysiology Indirect Idiosyncratic Direct BWH Medicine Chiefs @BrighamChiefs #DILI #DrugInduced #Liver #Injury #Pathophysiology #hepatology
Pathophysiology Indirect Idiosyncratic ... BrighamChiefs #DILI ... #DrugInduced #Liver ... Pathophysiology #hepatology
Drugs and Classes Associated with DILI and Type of Liver Injury #Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
Associated with DILI ... #Differential #DrugInduced ... #LiverInjury #Hepatology ... Pharmacology #Causes #DILI
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 Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Management of Idiosyncratic ... ) DILI Types: ... acetaminophen/APAP) • Idiosyncratic ... Liver #Injury #Idiosyncratic ... gastroenterology #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Liver Injury (DILI ... Diagnosis Algorithm DILI ... injury, Previous DILI ... #DrugInduced #Liver ... Diagnosis #Algorithm #hepatology
Drugs Commonly Implicated as Triggers of Drug Induced Thrombocytopenia #Diagnosis #Hematology #Thrombocytopenia #Differential #DrugInduced #Medications
Thrombocytopenia #Diagnosis #Hematology ... #Differential #DrugInduced
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
• Iatrogenic: DILI ... Diagnosis #causes #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
(>1000): • DILI ... Differential #Diagnosis #hepatology
Drug-Induced Thrombocytopenia The diagnosis of drug-induced thrombocytopenia can be made only by demonstrating resolution of thrombocytopenia once
#Diagnosis #Hematology ... #Differential #DrugInduced
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 Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Liver Injury (DILI ... Failure #Cirrhosis #Hepatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Induced Lupus (DIL ... rash is rare in DIL ... , SCLE-DIL (terbinafine ... for cutaneous DIL ... Lupusreference #druginduced
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