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diagnosis differential hepatology causes liver injury medications algorithm management pharmacology comparison dihs dress elevated hepatitis lupus rheumatology table transaminitis antibiotics
Drug-Induced Liver Injury - Pathophysiology Indirect Idiosyncratic Direct BWH Medicine Chiefs @BrighamChiefs #DILI #DrugInduced #Liver #Injury #Pathophysiology #hepatology
Pathophysiology Indirect Idiosyncratic ... BrighamChiefs #DILI ... #DrugInduced #Liver
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Management of Idiosyncratic ... Liver Injury (DILI ... ) DILI Types: ... acetaminophen/APAP) • Idiosyncratic ... Liver #Injury #Idiosyncratic
Drugs and Classes Associated with DILI and Type of Liver Injury #Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
Associated with DILI ... #Differential #DrugInduced ... Pharmacology #Causes #DILI
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 Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Liver Injury (DILI ... Diagnosis Algorithm DILI ... injury, Previous DILI ... hepatitis #DILI ... #DrugInduced #Liver
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
Vascular: Budd-chiari syndrome ... Sinusoidal obstruction syndrome ... • Iatrogenic: DILI
DRESS-associated drugs DRESS syndrome can be life threatening and it has a documented mortality rate of about
drugs DRESS syndrome ... The syndrome is ... #DRESS #Syndrome ... #DIHS #DrugInduced
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Induced Lupus (DIL ... rash is rare in DIL ... , SCLE-DIL (terbinafine ... for cutaneous DIL ... Lupusreference #druginduced
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
vein: Budd-chiari syndrome ... • Iatrogenic: DILI ... Unconjugated Bili ... > 90% of Total Bili ... • Gilbert's syndrome
Stevens Johnson Syndrome and Toxic Epidermal Necrolysis - Causative Medications and Level of Suspicion High Risk: Antigout:
Stevens Johnson Syndrome ... #Medications #DrugInduced
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 Neuroleptic Malignant Syndrome - Diagnosis Neuroleptic Malignant Syndrome is an idiosyncratic reaction to antipsychotic medications classically characterized
Neuroleptic Malignant Syndrome ... Neuroleptic Malignant Syndrome ... is an idiosyncratic ... NMS, Serotonin Syndrome ... , Stiff-person syndrome
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