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Cryoglobulinemia Classification Types

Type 1: Monoclonal IgM (rarely IgG/lgA)
 • Raynaud phenomenon, Digital ulcers/gangrene, Livedo reticularis, Hyperviscosity
Cryoglobulinemia Classification ... 1: Monoclonal IgM ... (rarely IgG/lgA ... 2: Monoclonal IgM ... Cryoglobulinemia #Classification
Subtypes of Serum Proteins

Pre-albumin (Transthyretin)
Albumin
Globulins
 • Alpha-1: Alpha-1 antitrypsin, Serum amyloid A, Ceruloplasmin, Corticosteroid-binding globulin (Transcortin),
Transferrin • Gamma: IgM ... , IgG, IgA, RF, ... Subtypes #algorithm #classification
Commonly Used Diagnostic Tests for Celiac Disease

Tissue transglutaminase (tTG) IgA antibodies
 - Most reliable noninvasive test
transglutaminase (tTG) IgA ... negative with IgA ... patients with IgA ... specific as tTG IgA ... Diagnosis #Workup #Table
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
antigen - IgG ... or IgM antibody ... Type Ill - IgG and ... Hypersensitivity #Types #Classification ... Diagnosis #Reactions #Table
Management of adult IgA Vasculitis (Henoch-Schönlein purpura) - Treatment algorithm for the management of IgAV patients
Management of adult IgA ... management of IgAV ... Management of IgA ... TerrierBen #IgA ... #Vasculitis #IGAV
Diagnosis of IgA Vasculitis (Henoch-Schönlein Purpura) - French Vasculitis Study Group 

1) Suggestive clinical manifestations
Diagnosis of IgA ... Elevated serum IgA ... vasculitis with IgA1 ... - Dominant IgA ... with vascular IgA
Burn Wound Assessment - Classification Table #Diagnosis #Clinical #Burn #Classification #Table #Epidermal #Superficial
Wound Assessment - Classification ... Table #Diagnosis ... Clinical #Burn #Classification ... #Table #Epidermal
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
IgA Vasculitis – ... immune response, IgA ... (GD-IgA1). ... -> Decr IgA serum ... -> adhesion of IgA
Celiac Disease Testing Algorithm
INDICATIONS FOR TESTING:  Nonspecific symptoms (iron-deficiency anemia, failure to thrive, fever, skin
Immunoglobulin A • tTG IgA ... • tTG IgG and ... DGP IgGa • EMA ... IgG by IFA • DGP ... IgA • HLA testing
Types of hypersensitivity reactions

Type I - lgE-Mediated, Within I Hour (Anaphylaxis)
Type II - IgG or IgM
Anaphylaxis) Type II - IgG ... or IgM Cytotoxic ... reactions #Types #Classification