7305 results
Endocarditis Signs

 - Osler's Node: Painful red fingers/toes ➔ immune
 - Janeway Lesion: Painless palms/soles ➔
fingers/toes ➔ immune ... JanewayLesion #Clinical
Type III Hypersensitivity: Pathogenesis and clinical findings
Definition: Small antigen-antibody complexes (produced from normal immune response to
Pathogenesis and clinical ... produced from normal immune ... a maladaptive immune
Primary Immune Deficiencies and their Clinical Presentations

#Primary #Immune #Deficiencies #Deficiency #Diseases #Presentations #Common #Overview
Primary Immune Deficiencies ... and their Clinical ... Presentations #Primary #Immune
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
PL12, EJ, OJ Immune ... Antibodies #MSAs #clinical
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Toxicity - Summary Clinical ... antisynthetase syndrome, immune-mediated ... muscle injury • Immune-mediated ... IU/I • SAMS clinical ... need to consider: immune-mediated
Acute Schistosomiasis: Katayama Fever
 • Most common in travelers and children
 • "Swimmers Itch" in the
and circulating immune ... Fever #diagnosis #clinical
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
can activate the immune ... the deposit of immune ... Immune-Mediated ... Syndrome: • Clinical
Myocarditis 

5 Principles of
Myocarditis:
1. Build clinical suspicion
2. Decide on EMBx
3. Manage acute cardiac injury
4. Manage chronic
Build clinical suspicion ... myocarditis Clinical ... anti-metabolite - Immune
Pathogenesis of meningitis 

Risk factors for pathogen entry include immunocompromised state (HIV positive, cancer, chemotherapy patients,
invasion, the immune ... complications and clinical ... Immune cells and
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
that disrupts immune ... accumulation of clinical ... Assessment • Clinical ... Others: Cellular immune