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management differential hematology syndromes bee cns fungal infections aids algorithm als amyotrophic anemia aplastic aspergillus cerebritis child chronic classification cll
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
splenomegaly, abnormal neurology ... Rheumatology ... involvement Sepsis - Immuno-compromise ... Pathway #Child #Peds ... #Pediatrics #Diagnosis
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
BEE Syndromes - Immune-mediated ... and treatment can ... Inflammatory causes ... BEE #Syndromes #neurology ... #differential #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
that disrupts immune ... Others: Cellular immune ... Drugs, Unknown cause ... Treatment: • ... #summary #rheumatology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
screening for disease ... with established disease ... normal in mild cases ... Avoid meds that ... #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Cerebrovascular Disease ... autoantibodies that will cause ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis
Invasive Aspergillus (IA) - Diagnosis and Management Aspergillus is ubiquitous in nature. Most invasive infections are caused
infections are caused ... impaired cellular immune ... vori Infectious Diseases ... #Management #treatment ... #fungal #infectiousdiseases
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
Non-inflammatory Causes ... Immune-mediated ... and less common diseases ... and treatment can ... BEE #Syndromes #neurology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... affects the skin, neurologic ... cognitive impairment, neurologic ... tract, and often causes ... #Rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
mutations) • Immune ... and petechiae Causes ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune ... cells can indicate disease ... microglobulin Treatment ... #workup #oncology ... #hematology
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