36 results
management differential hematology algorithm infections classification oncology syndrome vasculitis aids cardiology fungal hemophagocytic hiv hlh lung lymphohistiocytosis pediatrics workup abscess
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... Disease • Marrow ... Acquired • Immune ... #Algorithm #Causes ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... Hemolysis: • Immune-mediated ... Extravascular #Causes ... #hematology #anemia
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... With associated pulmonary ... involvement: Anti-GBM Disease ... #differential #diagnosis ... #algorithm #rheumatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... disorders • Celiac disease ... effect following treatment ... Iron deficiency anemia ... #Hematology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
FLAGS - In all cases ... Rheumatology ... involvement Sepsis - Immuno-compromise ... Pathway #Child #Peds ... #Pediatrics #Diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
that disrupts immune ... Others: Cellular immune ... Drugs, Unknown cause ... Treatment: • ... #summary #rheumatology
Visceral Leishmaniasis - Diagnosis and Management Summary Species: Leishmania donovani, Leishmania infantum, Leishmania chagasi Where: South Asia, East
cell-mediated immune ... Weight Loss • Can cause ... Lymphohistiocytosis • Anemia ... #management #treatment ... #infectiousdiseases
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
mutations) • Immune ... and petechiae Causes ... HCV - HIV • Immune ... Treatment: ... #diagnosis #management
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
reticularis Blood: Anemia ... inflammation tends to cause ... interstitial lung disease ... /pulmonary fibrosis ... signs #symptoms #diagnosis
Invasive Aspergillus (IA) - Diagnosis and Management Aspergillus is ubiquitous in nature. Most invasive infections are caused
infections are caused ... impaired cellular immune ... presentations: • Pulmonary ... vori Infectious Diseases ... #fungal #infectiousdiseases
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