10 results
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... lymphoproliferative disorders ... • Richter’s Syndrome ... syndrome • Smoldering ... workup #oncology #hematology
Helpful Clinical Features in Evaluating Bleeding Disorders
Age of onset
 • Neonate - in 20% of haemophilias,
Helpful Clinical ... tendency is acquired ... Marfan syndrome, ... osteogenesis imperfecta ... #Bleeding #Disorders
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
- Disorders of ... of a platelet disorder ... gingivitis or gingival leukemic ... von Willebrand syndrome ... Differential #Diagnosis #Hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
(CLL) - Summary ... in adults • Disorder ... immunophenotype Clinical ... uw_IMresidency #CLL ... hemeonc #diagnosis #management
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... Chronic Myelogenous Leukemia ... Cell Leukemia ... Neutropenia • Platelet Disorders ... #diagnosis #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
the secondary or acquired ... Clinical Presentation ... Fever is the main clinical ... purpura to mucosal bleeding ... #Diagnosis #Management
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... to impaired B-cell ... to 8 years Clinical ... severe community-acquired ... : • Nephrotic syndrome
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... ecchymoses, mucosal bleeding ... virus (EBV) • Leukemia ... Anemia #oncology #hematology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... • Secondary (Acquired ... Clinical Presentation ... malignancy, autoimmune disorder ... #Hematology #HemeOnc
Myelodysplastic syndromes current treatment algorithm 2018.

From Blood Cancer Journal, Published 24 May 2018

Myelodysplastic syndromes (MDS) are
Myelodysplastic syndromes ... Myelodysplastic syndromes ... acute myeloid leukemia ... an infection or bleeding ... importance of clinical