34 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Thrombocytopenia and Platelet Disorders ... pylori test (GI symptoms ... or if a primary hematologic ... disorder is suspected ... Causes #Workup #hematology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
Non-hemolytic Disorders ... Hyperbilirubinemia == Disorders ... examination; nonspecific symptoms ... • Disorder is ... Congenital #bilirubin #hepatology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... workup for specific symptoms ... organ-specific signs or symptoms ... #Eosinophil #Disorders ... Differential #diagnosis #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
lymphoproliferative disorder ... infection, autoimmune disorder ... (Cold-induced symptoms ... Monoclonal IgM Includes Disorders ... hemolytic #anemia #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... pattern of spread, B symptoms ... Lymphoproliferative #Disorders ... pathophysiology #Hematology
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
Lymphoproliferative Disorders ... regimen Signs/Symptoms ... adenopathy, B symptoms ... , unexplained hematologic ... Lymphoproliferative #Disorders
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA)

1) Is visual loss caused
acute ischemic disorder ... 2) Typical symptoms ... • Cephalic symptoms ... Constitutional symptoms ... GiantCellArteritis #GCA #Rheumatology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
distal to elbows/wrists ... thickening Signs and Symptoms ... Scleroderma #SSc #rheumatology ... diagnosis #signs #symptoms
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
leukemia in adults • Disorder ... lymphadenopathy 3) B symptoms ... Splenomegaly 5) Symptoms ... Constitutional symptoms ... Leukemia #oncology #hematology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Summary Framework Hematologic ... disorder characterized ... constitutional symptoms ... , or a related disorder ... proliferative disorder