61 results
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... syndrome (ST-HUS ... anemia" • HELLP syndrome ... #schistocytes #differential ... #diagnosis #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... uremic syndrome ... lymphoproliferative disorders ... Extravascular #Causes #differential ... #diagnosis #hematology
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS
represents
Systemic Signs (DRESS ... Syndrome): Formerly ... Images #Clinical #Dermatology ... #Syndrome #DrugReaction ... Eosinophilia #Legs #Photo
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS
represents
Systemic Signs (DRESS ... Syndrome): Formerly ... Images #Clinical #Dermatology ... #Syndrome #DrugReaction ... Eosinophilia #Photo
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
Inherited Non-hemolytic ... Conjugation == Gilbert Syndrome ... hyperbilirubinemia syndrome ... without evidence of hemolysis ... Congenital #bilirubin #hepatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... DIC/TTP/HUS - Hemolytic ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... #Diagnosis #hematology
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
thrombocytopenic purpura/hemolytic ... uremic syndrome ... thrombocytopenia, Hematology ... #Diagnosis #Differential
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Thrombocytosis - Differential ... iron deficiency, hemolysis ... Chronic inflammatory disorders ... Myelodysplastic syndrome ... Diagnosis #Causes #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Consider RBC membrane disorder ... #Anemia #Differential ... Algorithm #workup #hematology
Fever and Rash - Differential Diagnosis Framework
 • Viral: Measles, Infectious Mono (EBV, CMV), Acute HIV,
Fever and Rash - Differential ... Erythema Multiforme, DRESS ... , Sweet syndrome ... #Fever #Rash #Differential ... #Diagnosis #dermatology