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diagnosis differential ebm clinical management visualabstract causes algorithm criticalcare comparison hematology microscopy neurology nephrology pathology rheumatology treatment video myopathy ophthalmology
Myositis and Myopathies #ESR #CK #Differential diagnosis of myopathy #Inflammatory #myopathies #Dermatomyositis #muscle weakness #Polymyositis #Inclusion body myositis #Polymyalgia rheumatica #Fibromyalgia #Hypothyroid myopathy #Muscle stiffness #Drug-induced
Myositis and Myopathies ... #Inflammatory #myopathies ... Polymyositis #Inclusion ... #Drug-induced myopathies
Idiopathic Inflammatory Myopathies - Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Idiopathic Inflammatory Myopathies ... Syndrome (ASS), Inclusion ... #Inflammatory #Myopathies
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Myositis and Myopathies ... temporal arteritis Inclusion ... elevated CK, Biopsy: inclusions ... BostonChiefs #Myositis #Myopathies
Idiopathic Inflammatory Myopathies (IIM's) RASH + MUSCLE WEAKNESS → Consider idiopathic inflammatory myopathies (IIM's) • Overlap Myositis
Idiopathic Inflammatory Myopathies ... idiopathic inflammatory myopathies ... antisynthetase syndrome • Inclusion ... #Inflammatory #Myopathies
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
Inflammatory Myopathies ... discontinued Inclusion ... #Inflammatory #Myopathies
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
• Autoimmune: Inclusion ... • Metabolic myopathies ... polymyositis, inclusion ... certain drug-induced myopathies
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
- Metabolic Myopathies ... PROXIMAL AND DISTA: Inclusion
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
dermatomyositis, inclusion ... → Inflammatory myopathies
Common RBC Inclusions and Associations • Howell Jolly Bodies: Hyposplenism, Asplenism, Severe hemolytic anemia • Heinz
Common RBC Inclusions ... • Hemoglobin H Inclusion ... cell, MDS #RBC #Inclusions
Acute Myelopathies. #AcuteMyelopathies #Myelopathy #schema
Acute Myelopathies
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