8 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... presentation • Chronic ... Idiosyncratic #differential ... gastroenterology #algorithm ... gastroenterology #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Diagnosis Framework ... Cirrhosis • Chronic ... Hepatopathy • Acute ... (>1000): • DILI ... #Diagnosis #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis ... Algorithm DILI ... dechallenge • Acute ... #Injury #Diagnosis ... #Algorithm #hepatology
Appearance of Liver Lesions on Various Imaging Modalities
 • Computed Tomography (CT) - Arterial Phase, Portal
Appearance of Liver ... malformation, Infantile ... POCUS #radiology #differential ... #diagnosis #comparison ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Diagnosis Algorithm ... • Iatrogenic: DILI ... #diagnosis #algorithm ... #hepatology
Differential Diagnosis and Evaluation of Hyponatremia:
1) Identification of onset (acute vs. chronic)
2) Presence of symptoms (HA,
Differential Diagnosis ... vs. chronic) 2) ... history (cardiac, liver ... #EM #IM #Nephro ... #Algorithm #Ddxof
Appearance of Liver Lesions on Magnetic Resonance Imaging (MRI) - T2, T1 precontrast, T1 portal venous,
Appearance of Liver ... malformation, Infantile ... MagneticResonance #radiology #differential ... #diagnosis #comparison ... #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
> 2 • NASH, Chronic ... injury: > 3 • Chronic ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis