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hepatology differential algorithm primary causes albumin antibodies gradient pbc rheumatology saag alkaline alp ana antinuclear associations autoantibodies diseases elevation hepatitis
Diagnosis of ascites according to the serum ascites albumin gradient (SAAG) SAAG ≥ 1.1: - Ascitic protein
Diagnosis of ascites ... protein ≤ 2.5 g/dL: Cirrhosis ... , Massive liver ... SAAG < 1.1: Biliary ... #differential #diagnosis
Causes of Ascites - Differential Diagnosis Algorithm Portal Hypertension - Prehepatic: • Portal vein thrombosis • Splenic
- Differential Diagnosis ... - Hepatic: • Cirrhosis ... disease • Acute liver ... failure • Primary biliary ... cholangitis •
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Cirrhosis (PBC) ... /Liver failure ... Symptoms: • 50 ... #Cirrhosis #PBC ... #cholangitis #diagnosis
The 6 C’s of Primary Sclerosing Cholangitis (PSC) PSC is a chronic, cholestatic, immune-mediated disease characterized by
to multi-focal biliary ... asymptomatic at diagnosis ... colorectal and hepato-biliary ... Care focuses on symptom ... #diagnosis #management
Ascites - Differential Diagnosis Chronic liver disease (cirrhosis or chronic hepatitis) - 80% Underlying malignancy - 10% Congestive heart
Ascites - Differential ... Diagnosis Chronic ... liver disease ( ... Fitz-Hugh-Curtis syndrome ... Failure, Pancreatic, Biliary
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... Highest • Bone • Liver ... Most common symptoms ... Cholangitis (PBC ... - Other biliary
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary ... Cirrhosis - Diagnosis ... Algorithm Symptoms ... Liver biopsy findings ... #Biliary #Cirrhosis
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
- Differential Diagnosis ... Non-Malignant • Fatty Liver ... • Budd-Chiari Syndrome ... • Primary Biliary ... Cirrhosis #Hepatomegaly
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
- Differential Diagnosis ... of portal HTN: ascites ... and hepatorenal syndrome ... portal HTN: • Ascites ... pregnancy • Primary biliary
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... vein: Budd-chiari syndrome ... , PSC, IgG4, HLH ... hepatitis: < 1 • Cirrhosis ... • Gilbert's syndrome
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