34 results
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
Evaluation and Management ... of Sickle Cell Crises ... Clinical Manifestations ... and Management ... #Hematology #SickleCell
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
>10 mmHg - clinically ... : • Cardiac causes ... sarcoidosis) • Liver ... metastasis • Fatty liver ... #hepatology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
and hematologic ... If other causes ... hemochromatosis; HIC, hepatic ... algorithm #diagnosis #management ... #hepatology #gastroenterology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... +++ (Plt, Hb), Hepatic ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Lymphohistiocytosis (HLH ... : Overwhelming clinical ... lymph node, or liver ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Portal venous gas on hepatic ultrasound: A concerning finding in the critically ill patient that should
venous gas on hepatic ... variety of other causes ... venousgas #ultrasound #hepatology ... #liver #pocus # ... clinical #air
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
• Secondary Causes ... deficiency • Liver ... Cholesterol emboli • Septic ... Differential #Diagnosis #hematology ... #rheumatology #
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Causes include : ... (e.g. heparin contamination ... thrombin inhibitors, heparin ... • Reduced liver ... #differential #hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Algorithm Vascular Causes ... Injury: • Hepatic ... Venoocclusive disease • Hepatic ... PBC, PSC, IgG4, HLH ... diagnosis #algorithm #hepatology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
 - HLH-94 Protocol
    • Dexamethasone
Treatment Primary HLH ... steroids • In mild cases ... Options for severe cases ... #Treatment #management ... #hematology