11 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Injury (DILI) ... #differential # ... Diagnosis #Management ... gastroenterology #hepatology
Table of Causes of Acute Liver Injury
#Diagnosis #Hepatology #Acute #Liver #Injury #Causes #Differential #Incidence #Table #Failure
Table of Causes ... of Acute Liver Injury ... #Diagnosis #Hepatology ... #Acute #Liver # ... Differential #Incidence
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - Differential ... Diagnosis Framework ... (>1000): • DILI ... injury) • Ischemic ... #Diagnosis #hepatology
Appearance of Liver Lesions on Various Imaging Modalities
 • Computed Tomography (CT) - Arterial Phase, Portal
malformation, Infantile ... POCUS #radiology #differential ... #diagnosis #comparison ... #table #appearance ... #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Injury (DILI) ... Hepatitis Procedures Management ... Failure #Cirrhosis #Hepatology ... gastroenterology #management ... #diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential ... Diagnosis Algorithm ... • Iatrogenic: DILI ... #hepatology
Appearance of Liver Lesions on Computed Tomography (CT) - Arterial Phase, Portal Venous Phase and Delayed
malformation, Infantile ... CT #radiology #differential ... #diagnosis #comparison ... #table #appearance ... #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Unconjugated Bili ... > 90% of Total Bili ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Appearance of Liver Lesions on Magnetic Resonance Imaging (MRI) - T2, T1 precontrast, T1 portal venous,
malformation, Infantile ... MagneticResonance #radiology #differential ... #diagnosis #comparison ... #table #appearance ... #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
10x ULN), ↑Tbili/Dbili ... infiltration) Differential ... Diagnosis: Viral ... #Pregnancy #hepatology ... obstetrics #obgyn #diagnosis