8 results
Differentiating NBTE from Infective Endocarditis
No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
pathognomonic signs ... Blood cultures/serology ... heart valves • MRI ... brain for cerebral ... Blood cultures/serology
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
Compatible syndrome + MRI ... granulomatosis: • EBV-associated ... RingEnhancing #Lesions #Brain ... #causes #radiology ... #neurology
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
- Differential Diagnosis ... Algorithm Red ... Space-occupying brain ... lesion • CNS infection ... #Algorithm #neurology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
early stages of infection ... through the blood-brain ... similar to PML, but MRI ... Diagnosis: MRI ... dementia #AIDS #Neurology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Lack of UMN/LMN signs ... Neoplastic: Malignancy-associated ... aminotransferases • Serology ... EMG) studies • MRI ... #neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
parietal lobes of the brain ... may precede the neurologic ... fluctuations PRES-Associated ... : • Infection, ... #management #neurology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Associated with: ... Myotonic dystrophy - Brain ... - Peek sign ... precipitated by: Drugs, infection ... #management #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Direct microbial infection ... • Bilateral signs ... ruled out • Brain ... brain and/or optic ... #management #neurology