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diagnosis disease hematology treatment differential symptoms vasculitis activation apml arteritis arthritis autoimmune behcet cabcde calcium capillary chagas clarksons classification coronavirus
Pediatric Inflammatory Multisystem Syndrome Temporally associated with SARS-CoV-2 infection (PIMS-TS) Clinical features all: fever > 101.3 F most: oxygen
Pediatric Inflammatory ... Multisystem Syndrome ... with SARS-CoV-2 infection ... some: abdominal pain ... coronavirus #diagnosis #Signs
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... Diagnosis: HLH signs ... agent are the main ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... • Fever is the main ... SLE], AOSD) • Infection ... #Diagnosis #Management ... #Hematology #Rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
+/- myocardial infarction ... Nonsurgical abdominal pain ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... ischemia, bowel infarction ... WBC >100k, + lab signs ... TLS #diagnosis #management ... #hematology
Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
knees, shoulders Signs ... inflammatory) • joint pain ... corticosteroid injections ... Arthritis #diagnosis #management ... #rheumatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... thickening • Osteitis: pain ... causes such as infectious ... #Rheumatology # ... diagnosis #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... effusions, weight gain ... Differential Diagnosis: Infection ... APML #diagnosis #management ... #hematology #oncology
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary Chagas disease (American trypanosomiasis) is an infectious
Diagnosis and Management ... trypanosomiasis) is an infectious ... family Route of infections ... Romana's sign ... 80%) (abdominal pain
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... vasculitis vs infection ... claudication: pain ... them, but urgent rheumatology ... Symptoms #Diagnosis #Management
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