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diagnosis management neurology differential toxicology cardiotoxicity msk oncology pulmonary syndrome acute aids als amiodarone amyotrophic angina anthracycline associated barre bcvi
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
spinal artery injury ... function below injury ... Syndromes #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics #neurology
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
Induced Muscle Toxicity ... any time during treatment ... Direct muscle injury ... Risk of muscle injury ... Statin #muscle #toxicity
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
: • Triad of symptoms ... urine • Other symptoms ... Treatment: ... Treatment of underlying ... #nephrology
Metformin Associated Lactic Acidosis (MALA) Pathophysiology of MALA - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... and acute kidney injury ... also includes symptoms ... LacticAcidosis #Toxicity
Noncardiogenic Pulmonary Edema - Differential Diagnosis Framework NCPE Pathophysiology: Noncardiogenic pulmonary edema occurs because of excessive pulmonary capillary
Framework NCPE Pathophysiology ... • Salicylate toxicity ... contents • Head injury ... Traumatic brain injury ... differential #diagnosis #cardiology
Reported Mechanisms and Toxicity of Investigational Treatments for SARS-COV-2 Chloroquine and Hydroxychloroquine • Mechanisms: Interference with ligand
Mechanisms and Toxicity ... Investigational Treatments ... 3 response • Toxicity ... hearing loss, GI symptoms ... acidosis, renal injury
Iron Deficiency in Heart Failure Pathophysiology: Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... functional ID) Treatment ... improvement in symptoms ... diagnosis #management #cardiology
Vasospastic (Prinzmetal) Angina Definition / Epidemiology: • Rest angina attributed to coronary artery vasospasm. • Patients often
Pathophysiology: ... microvascular injury ... tests in cath lab Treatment ... Prinzmetal #Angina #cardiology
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
cytotoxic lung injury ... starting amiodarone treatment ... gradually with symptoms ... Improvement in symptoms ... macrophages Treatment
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Etiology: • Pathophysiology ... Neurological symptoms ... Medication/Drug toxicity ... epilepticus Treatment ... underlying cause • Treatment
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