810 results
Post-TAVR Suicide Left Ventricle
Pre-TAVR: High afterload from aortic stenosis leads to compensatory left ventricular hypertrophy and
through TAVR: ↓ Inotropy ... diagnosis #management #pathophysiology
Adrenoceptor Actions
α1
 • Vascular smooth muscle - Contraction
 • Genitourinary smooth muscle - Contraction
 • Intestinal
• Heart - ↑ Inotropy ... Chronotropy and inotropy ... #pharmacology #pathophysiology
Vasopressors - Charted by Vasoconstriction, Vasodilation, and Inotropy
 - Dobutamine
 - Milrinone 
 - Vasopressin
 -
Vasodilation, and Inotropy ... #Vasodilation #Inotropy ... Pharmacology #Visual #Inotropes
Pressors and Inotropes

Norepinephrine
 • alpha1 > beta 1
 • Increase SVR > Inotropy
Vasopressin
 • V1
 •
Pressors and Inotropes ... Increase SVR > Inotropy ... 2, alpha 1 • Inotropy ... beta 1 and 2 • Inotropy ... inhibitor • Inotropy
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
force (negative inotropy ... Classification #Classes #pathophysiology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
force (negative inotropy ... Classification #Classes #pathophysiology
Clinician's Pocket Guide to Vasopressors - Receptor Profiles and Hemodynamic Parameters
 • Systemic Vascular Resistance -
Circulatory pressure • Inotropy ... table #receptors #inotropes
Vasopressors Table 
Rough properties by Target Receptor, Heart Rate/Inotropy, Systemic Vascular Resistance, Cardiac Output, Blood Pressure,
Receptor, Heart Rate/Inotropy ... Management #Comparison #Inotropes
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
Vasopressors and Inotropes ... Increases BP, SVR, not inotropic ... vasoconstriction, SVR Inotropes ... #Vasopressors #Inotropes
Calcium Channel Blockers - Dihydropyridines vs Non-Dihydropyridines
Dihydropyridines (amlodipine, felodipine, nifedipine, nicardipine)
 • SVR: Decrease
 • Inotropy:
SVR: Decrease • Inotropy ... SVR: Decrease • Inotropy