18 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
that disrupts immune ... accumulation of clinical ... Assessment • Clinical ... Treatment: • ... #management #treatment
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... (specifically immune ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Invasive Aspergillus (IA) - Diagnosis and Management
Aspergillus is ubiquitous in nature. Most invasive infections are caused
are caused by members ... impaired cellular immune ... HIV/AIDS, CGD) Clinical ... Diseases Fellows ... #Management #treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... underlying genetic immune ... #management #treatment ... #hematology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Inflammatory Syndrome ... worsening of that disease ... opportunistic infection ... infection Treatment ... #Management
IDSA Recommendations for Treating Coccidiodomycosis in HIV-AIDS
Treating Mild Infections (Such As Focal Pneumonia or asymptomatic patients
(Diffuse Pulmonary ... • Use until clinical ... #management #opportunistic ... #infections #HIVAIDS ... #pharmacology
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Relapsing-remitting course +++ Clinical ... filling +++ (risk of pulmonary ... of infections) ... #diagnosis #management ... #rheumatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... and petechiae Causes ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
IDSA Recommendations for Preventing and Managing Microsporidiosis in HIV-AIDS
Preventing Chronic Microsporidiosis:
 • Because chronic microsporidiosis occurs
should prevent the disease ... optimize ART with immune ... #management #opportunistic ... #infections #HIVAIDS ... #pharmacology
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... Caused by intrapulmonary ... shunt (Type 2) Clinical ... #diagnosis #management ... #treatment #hepatology