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diagnosis management differential pharmacology clinical endocrinology diabetes algorithm causes comparison pathophysiology table treatment nephrology cardiology ketoacidosis hyperkalemia pocus diabetic dm2
Pathophysiology and Effects of Insulin Deficiency #Insulin #Deficiency #DKA #Ketoacidosis #Diabetes #Pathophysiology #Endocrinology
and Effects of Insulin ... Deficiency #Insulin ... #Deficiency #DKA
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS) Absolute Insulin deficit: - Type I DM:
Ketoacidosis (DKA ... HHS) Absolute Insulin ... Type I DM: No insulin ... stresses that ↑ insulin ... Polydipsia #dka
Pathogenesis of Diabetic Ketoacidosis - Insulin deficiency or severe insulin insensitivity #DKA #Pathophysiology #Endocrinology #Diabetes #Ketoacidosis
Ketoacidosis - Insulin ... deficiency or severe insulin ... insensitivity #DKA
DKA vs HHS - Think of DKA and HHS on a spectrum of hyperglycemic emergencies -
DKA vs HHS - Think ... of DKA and HHS ... emergencies - HHS = insulin ... restart any home insulin ... look like overlap DKA
Pathogenesis and Pathophysiology of Diabetic Ketoacidosis (DKA) DKA is a result of an absolute or relative insulin
Ketoacidosis (DKA ... ) DKA is a result ... Insulin is the primary ... the absence of insulin ... In DKA, the normal
SGLT2 Inhibitors and Euglycemic DKA Risk factors for euglycemic DKA in those on an SGLT2i include: •
and Euglycemic DKA ... for euglycemic DKA ... • Increased insulin ... and surgery) • Insulin ... SGLT2 #Euglycemic #DKA
Ketosis Disorders Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
produce endogenous insulin ... ketoacidosis (DKA ... caused by complete insulin ... • Euglycemic DKA ... HHS) - partial insulin
DKA DIAGNOSTIC CRITERIA: 1. Serum glucose >250 mg/dL 2. Arterial pH <7.3 3. Serum bicarbonate <18 mEq/L 4. At least
DKA DIAGNOSTIC CRITERIA ... 10% to 30% of DKA ... Continue insulin ... and subcutaneous insulin ... #DKA #EDKA #Insulin
Events Resulting from Acute Insulin Deficiency in Type 1 Diabetes Mellitus If left untreated, insulin deficiency may
Resulting from Acute Insulin ... left untreated, insulin ... #DKA #Ketoacidosis ... Pathophysiology #Insulin
Pathophysiology of Euglycemic DKA in SGLT2 Inhibitors • Kidney: Glycosuria, Natriuresis, ↑ Ketone bodies reabsorption •
of Euglycemic DKA ... • Pancreas: ↓ Insulin ... → Euglycemic DKA ... #Euglycemic #DKA
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