15 results
Diabetic Ketoacidosis 
Management Priorities
1. Fluids 
2. Insulin 
3. Potassium 
4. Acidosis 
5. Re-establish oral fluids,
Diabetic Ketoacidosis ... Potassium 4. ... Acidosis 5. ... #DKA #Diabetic ... #Ketoacidosis #Diabetes
Insulin Dosing Basics - Initiating Insulin for T2DM and Converting Insulin Products 

Insulin dosing can be
For type 2 diabetes ... for type 2 diabetes ... run into patient cases ... Basics #Dosing #Conversion ... #Prescribing #Pharmacology
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... • Increases insulin-mediated ... hypoglycemia • Low ... causing lactic acidosis ... #Summary #DM2 #diabetes
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... Defining the cause ... Renal tubular acidosis ... Ureterosigmoidostomy, Diabetic ... #nephrology #potassium
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
alkalosis • Normal/low ... • Diabetic ketoacidosis ... the indicated causes ... of sodium and potassium ... urine #Algorithm #nephrology
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Causes of High-anion ... Causes of High-anion ... Ketoacidosis: Diabetic ... Potassium-sparing ... #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
(Uncontrolled diabetes ... - Metabolic acidosis ... paralysis - Insulin ... differential #diagnosis #causes ... #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
(Uncontrolled diabetes ... - Metabolic acidosis ... paralysis - Insulin ... differential #diagnosis #causes ... #nephrology
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
Ketosis (SK), acidosis ... also have Lactic Acidosis ... drips unless also diabetic ... both conditions, low ... provided the starting potassium
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... Piretanide Potassium ... Aquaretics (not a diuretic ... #nephrology #conversion ... loop #thiazide #classes