11 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... Diagnosis Algorithm ... disturbance (obstructed liver ... • Liver (80%) ... #hepatology
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
(LFTs) - Normal ... , lungs, RBCs Alkaline ... , bone, placenta ... Interpretation #diagnosis ... #hepatology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver ... Adult form: Less ... Low ALP in adult ... Hyophosphatasia #hepatology ... #diagnosis
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... ALP, alkaline phosphatase ... aminotransferase; BMI, body ... #Algorithm #Hepatology ... #Differential #
Causes of Hyperferritinemia - Differential Diagnosis
Ferritin > 1000
Ferritin is the storage form of iron. Increased hepcidin
Diagnosis Ferritin ... be used by the bone ... is made in the liver ... HLH or Adult Onset ... Hematologic Malignancy
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Epidemiology: young adults ... the spleen or liver ... also arise in normal ... #differential # ... hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Diagnosis Algorithm ... hemolysis) • ALP: Bone ... #diagnosis #algorithm ... #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
cholestasis → Cirrhosis/Liver ... PBC Labs: • Alkaline ... or higher • Liver ... bile ducts Differential ... #workup #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
- If both are normal ... hemolysis) • ALP: Bone ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
history • Young adults ... lymph node biopsy (diagnostic ... Immunohistochemical studies (to differentiate ... anymore • Routine bone ... classification #hematology