Liver Function Tests (LFTs) - Normal Values and Interpretation Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal muscle, kidneys Aspartate aminotransferase (AST/SGOT) - Liver, cardiac & skeletal muscle, kidney, brain, pancreas, lungs, RBCs Alkaline phosphatase (AlkP) - Liver, bone, placenta, kidney, intestines Gamma-glutamyl-transpeptidase (GGT) - Liver, biliary epithelium, kidney, seminal vesicles, pancreas, spleen, heart, brain, NOT in bone 5'-nucleotidase - Liver, intestine, brain, heart, blood vessels, endocrine pancreas, NOT in bone Total bilirubin (TBili) Direct bilirubin (Conjugated/DBili) - Biliary obstruction, intrahepatic cholestasis, hepatocellular injury, genetic (?) Indirect bilirubin (Unconjugated) - Overproduction (hemolysis) impaired uptake (drugs, shunts) impaired conjugation (Gillbert, Crigler-Najjar) Albumin - Plasma (almost exclusively made in liver) Prothrombin Time (PT) - Marker of vitamin k- associated clotting factors International Normalized Ratio (INR) - Standardization of prothrombin time across labs By Dr. Khushboo Gala @LouLectures #Liver #Function #Tests #LFTs #Laboratory #Values #Interpretation #diagnosis #hepatology
