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differential abnormal prolonged bleeding bruising comparison deficiencies deficiency disseminated hemostasis intravascular management summary treatment
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
PT and/or aPTT ... Acquired deficiency ... (DIC) c. ... #Causes #diagnosis ... #differential #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... dysfunction (16%) • Shock ... INR < 2.3 - APTT ... #diagnosis #causes ... treatment #management #hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
PT and the aPTT ... intravascularcoagulation (DIC ... #Causes #diagnosis ... #differential #hematology ... #coagulation
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
of Factor IX Acquired ... Post-partum • Acute DIC ... - Septic shock, ... #comparison #diagnosis ... #hematology #deficiency
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
- Differential Diagnosis ... inhibitor of a coagulation ... discern these causes ... disease • Acute DIC ... #Hematology
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