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C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
(CDI) - Diagnosis ... Toxic Megacolon, Shock ... can be community-acquired ... Ileus, Megacolon, Shock ... #treatment #infectiousdiseases
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... Purtilo (XLP) Acquired ... Drugs, Unknown cause ... Treatment: • ... #management #treatment
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
- Differential Diagnosis ... Antimicrobial treatment ... is generally required ... Demyelinating disease caused ... opportunistic #InfectiousDiseases
Capnocytophaga
Pathogen: Capnocytophaga
 • 9 species, C. canimorsus responsible for the majority of infections
 • Gram-negative rod,
the majority of infections ... malaise • Septic shock ... Treatment: • 50% ... microbiology #zoonotic #infectiousdiseases ... #treatment
Fusarium Infections
Acquired through:
1. Inhalation of airborne conidia > germinates > blood > disseminated
2. Trauma (implantation with
Acquired through ... BCx+ in -40% of cases ... disease: • Optimal treatment ... #infectiousdiseases ... #diagnosis #management
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... Complex (MAC): • Acquired ... Advanced HIV (CD4 ... Diagnosis Of NTM ... #infectiousdiseases