13 results
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
- Pharmacology ... first agent in shock ... • Higher doses cause ... /cGMP • Causes ... #Pharmacology #
Common Vasopressors and Inotropes
Norepinephrine (NE)
 - Indication: Distributive shock (1st line for septic shock), Cardiogenic shock
Vasopressors and Inotropes ... Bradyarrhythmias, Some cases ... - Indication: Can ... #Vasopressors #Inotropes ... comparison #table #pharmacology
Clinical Management for Three Common Causes of Shock 
HEMORRHAGIC SHOCK
 • Ensure adequate ventilation and oxygenation.
for Three Common Causes ... of Shock HEMORRHAGIC ... SHOCK • Ensure ... vasopressor or inotropic ... • Consider intraaortic
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
undifferentiated shock ... is in impending shock ... ill patient with shock ... perfusion - shock ... vasopressors, or inotropes
Antibiotics for severe community-onset pneumonia 

Atypical coverage always 

- Usually azithromycin 500 mg daily 

- Doxycycline
piperacillin-tazobactam Septic Shock ... only in selected cases ... #Community #Acquired ... #Pneumonia #CAP
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
correct profile can ... essentially Cardiogenic Shock ... patients need inotrope ... the determined cause ... icu #clinical #pharmacology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... leading to slow Ca ... force (negative inotropy ... Antiarrhythmics #Pharmacology ... Classification #Classes
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Action, ↑ EFR & AP ... and Ca++ current ... force (negative inotropy ... Vaughan #Williams #Pharmacology ... Classification #Classes
Naloxone - Toxicology

Adult starting dose:
 - 0.4 mg IV/IM/IO/SQ for non-opioid dependent patients
 - 0.04 mg
search for other causes ... an infusion is required ... infusion in an adult can ... Toxicology #Management #Pharmacology
Medications Used in the Abortive Treatment of Ongoing Seizure Activity in the Emergency Department

INITIAL THERAPY
 -
Medications Used in the Abortive ... Phenytoin - May cause ... hemodynamic support required ... 4.8 mg/kg/hr #Abortive ... Medications #Neurology #Pharmacology