9 results
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... fractures of feet, thigh ... collection with EDTA Pathophysiology ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
High Output Heart Failure - Pathophysiology and Differential Diagnosis
Obesity - Systemic Vasodilation, Vasoactive Adipokines
Arteriovenous Fistula -
High Output Heart ... Failure - Pathophysiology ... and Differential Diagnosis ... Congenital (e.g., HHT), Acquired ... #cardiology #causes
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... psychiatric changes), high ... evaluation: not required ... in all patients ... #hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... PBC Labs: • Alkaline ... obstruction • ALP ... #workup #hepatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
- Differential Diagnosis ... THROMBOSIS • Acquired ... considered in all ... Venous #Arterial #pathophysiology ... #hematology #differential
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Griscelli, Purtilo (XLP ... ) Acquired HLH: ... Drugs, Unknown cause ... treatment #summary #rheumatology
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
and Pathophysiology ... Hyperdynamic circulation/High ... • Mitchell et al ... #Pathophysiology ... #causes #cardiology
Perhaps quite too often, the knee-jerk reaction to an elevated Troponin is to call our friends
extraction is so high ... heart (Sepsis, Shock ... treat the primary cause ... “one size fits all ... #diagnosis #management
Perhaps quite too often, the knee-jerk reaction to an elevated Troponin is to call our friends
extraction is so high ... heart (Sepsis, Shock ... treat the primary cause ... “one size fits all ... #diagnosis #algorithm