23 results
T-LGL leukemia - T-CeIl Large Granular Lymphocytic Leukemia
Clinical
 - Persistent (>6mo) lymphocytosis (2-20k) with proven clonality
- Positive: CD2 ... , CD3, CD8 - Loss ... of CD5 and/or CD7 ... be CD4+ but this ... hemepath #pathology #diagnosis
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Difficile Infection (CDI ... Toxic Megacolon, Shock ... Perforation) Pathophysiology ... post-ABx, but can ... be community-acquired
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
- Differential Diagnosis ... Disease by CD4 ... Count: Any CD4 ... Seasonal influenza CD4 ... Blastomycosis CD4
Community Acquired Pneumonia - Severity and Prognosis
Criteria for Severe CAP - Severe CAP present in 1
Community Acquired ... Pneumonia - Severity ... criteria: Septic shock ... #Community #Acquired ... #severe #psi #diagnosis
Community Acquired Pneumonia - Presenting Features
 • History in favor of CAP: Dyspnea, Cough, particularly if
Community Acquired ... Pneumonia - Presenting ... criteria: Septic shock ... #Community #Acquired ... #Pneumonia #diagnosis
Intestinal Hookworm Life Cycle
1) Eggs in feces
2) Rhabditiform larva hatches
3) Development to filariform larva in environment
4)
Ancylostoma spp. larvae can ... Intestinal #lifecycle #diagnosis ... #pathophysiology ... infectiousdiseases #cdc
Cysticercosis - Taenia solium Life Cycle
1) Eggs or gravid proglottids in feces and passed into environment.
2)
cysticerci. 5) Humans acquire ... TaeniaSolium #LifeCycle #diagnosis ... #pathophysiology ... infectiousdiseases #cdc
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
auto-reactive B and CD ... Increased ESR and CRP ... RheumaticFever #pathophysiology ... #diagnosis #signs
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... Auto-amplification loop Diagnosis ... Purtilo (XLP) Acquired ... Lymphohistiocytosis #diagnosis
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
ART ↑ improves CD4 ... low pretreatment CD4 ... occur at any CD4 ... an increase in CD4 ... Depends On: • CD4